Lesley-Ann Brandt was born 2 December 1981 in Cape Town. She is coloured and has a mix of ancestry including East Indian, Dutch, German, And Spanish. As a youngster, Brandt was a very active, competitive and talented child who loved sports and does not hold back in playing.

She played competitive field hockey and also enjoys yoga and baseball. Besides English, Lesley-Ann also speaks Afrikaans fluently. Not much is known about her educational history, although she is believed to have completed her Bachelor’s level studies.

In her late teenage years, her family immigrated to Auckland, New Zealand where she easily adapted to her new environment and soon got a job. She worked in retail sales prior to landing a job as an IT recruitment consultant. Besides, she also worked for Red Bull as a promo girl. The South African export soon landed some modelling gigs and was cast in a number of New Zealand television advertisements. Afterwards, she was scouted by local casting directors who introduced her to the world of acting. She made her acting debut on a soap opera named Shortland Street in 2007. She later studied acting and was trained in the Meisner technique in 2008.

Then, she took up roles in a number of other TV series such as the sci-fi series This Is Not My Life and her first main role came in Diplomatic Immunity alongside Craig Parker who later became her close friend. However, it was her portrayal of Naevia, a slave girl in the Starz hits, Spartacus: Blood and Sand and Spartacus: Gods of the Arena that marked her breakthrough in the acting scene. Her performance endeared her to audiences as well as brought her to the international spotlight.

She also appeared in the New Zealand coming-of-age feature film The Hopes & Dreams of Gazza Snell, a film about the victim of a kart racing accident, and had a guest role in Legend of the Seeker in 2010. In 2011, Leslie-Ann Brandt had a number of guest roles in works such as CSI: NY alongside Cynthia Addai-Robinson who replaced her as Naevia in the Spartacus series and in Memphis Beat. That same year, she was featured in the film InSight as nurse Valerie Khoury and had a lead role in Zombie Apocalypse, Syfy’s highest-rated original feature for 2011 as Cassie. The film also starred Ving Rhames and Taryn Manning.

Brandt’s other credits include A Beautiful Soul (2012), Drift (2013) opposite Sam Worthington, the third season of Single Ladies (2014) as Naomi Cox, Fox’s Gotham (2014) as Larissa Diaz/Copperhead and Lamia in The Librarians. She starred opposite Richard Dreyfuss, Danny Glover, and Jon Heder in the dark comedy film Killing Winston Jones. Lesley-Ann was cast as Mazikeen “Maze” in the Fox TV series Lucifer in 2015. Her character is a fiercely strong yet vulnerable, pansexual demon who follows the titular character, Lucifer, played by Tom Ellis, out of hell to work as his adjutant.